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Activated clusters (red dots) in temporal lobe of normal human brain during propofolinduced anesthesia revealed by functional magnetic resonance imaging. See Zhang et al., on page 1985, in this issue.
Propofol has been used for many years but its functional target in the intact brain remains unclear. In the present study, we used functional magnetic resonance imaging to demonstrate blood oxygen level dependence signal changes in the normal human brain during propofol anesthesia and explored the possible action targets of propofol. Ten healthy subjects were enrolled in two experimental sessions...
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