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BackgroundAngiogenesis plays a pivotal role in splanchnic hyperaemia and portosystemic collateral formation in cirrhosis. Endothelin‐1 (ET‐1), an endothelium‐derived vasoconstrictor, has also been implicated in the pathogenesis of cirrhosis and portal hypertension.
DesignThis study aimed to survey the influences of ET‐1 in cirrhosis‐related angiogenesis. Common bile duct ligation was performed on...
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