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Applying the molecular dynamic simulation, we have studied the interaction between two groups of adhesion-proteins and Cu (100) surface by the “double-layer” model. The two groups of proteins are respectively Mefp-1, Mefp-3, Mefp-5, and Mefp-1-Cl, Mefp-3-Cl, Mefp-5-Cl after modification by HOCl. The results show: the interaction energy per mole or per unit mass for the protein & Cu(100) is larger...
The adhesion properties of both hepatocytes and hepatocellular carcinoma (HCC) cells onto the Coll IV/Laminin coated surface were measured by means of micropipette aspiration technique. Further cytoskeletal agents of colchicine and cytochalasin D were tested for their effects on adherence to Coll IV/Laminin coated dishes. The results showed: cytochalasin D, which inhibits microfilament polymerization,...
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