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IL-33 is a multifunctional cytokine in immune regulation that activates Th1 cells, Th2 cells, CD8 + T cells and NK cells. Our study showed that transgenic expression of IL-33 attenuated tumor metastasis in the B16 melanoma and Lewis lung carcinoma (LLC) metastatic models. The percentages and cytotoxicity of CD8 + T cells and NK cells and their infiltration into the tumor tissues were...
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