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Here, we used knock‐in (KI) mice that have ethanol‐insensitive alpha 1 glycine receptors (GlyRs) (KK385/386AA) to examine how alpha 1 GlyRs might affect binge drinking and conditioned place preference. Data show that tonic alpha 1 GlyR‐mediated currents were exclusively sensitive to ethanol only in wild‐type mice. Behavioral studies showed that the KI mice have a higher intake of ethanol upon first...
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