Search results for: Markus Knuf

Items from 1 to 20 out of 43 results

article

Association of viral load with TRAIL, IP‐10, CRP biomarker signature and disease severity in children with respiratory tract infection or fever without source: A prospective, multicentre cohort study

Cihan Papan, Alberto Argentiero, Ortwin Adams, Marian Porwoll, more

Journal of Medical Virology > 95 > 1 > n/a - n/a

Background To investigate the association of viral load (VL) with (i) tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL), interferon gamma‐induced protein‐10, C‐reactive protein, and a combinatorial score (BV score), and (ii) clinical severity. Study Design In this prospective, multicentre cohort substudy, children with respiratory tract infection or fever without source were enrolled...

article

German evidence and consensus‐based (S3) guideline: Vaccination recommendations for the prevention of HPV‐associated lesions

Gerd E. Gross, Ricardo N. Werner, Gabriela L. Avila Valle, Markus Bickel, more

JDDG: Journal der Deutschen Dermatologischen Gesellschaft > 19 > 3 > 479 - 494

Anogenital and oropharyngeal infections with human papilloma viruses (HPV) are common. Clinically manifest disease may significantly impact quality of life; the treatment of HPV‐associated lesions is associated with a high rate of recurrence and invasive neoplasms, such as cervical, anal, vulvar, penile, and oropharyngeal cancers, which are characterized by significant morbidity and mortality. Vaccination...

article

Evidenz‐ und konsensbasierte (S3) Leitlinie: Impfprävention HPV‐assoziierter Neoplasien

Gerd E. Gross, Ricardo N. Werner, Gabriela L. Avila Valle, Markus Bickel, more

JDDG: Journal der Deutschen Dermatologischen Gesellschaft > 19 > 3 > 479 - 494

Anogenitale und oropharyngeale Infektionen mit humanen Papillomviren (HPV) sind weit verbreitet. Im Fall einer klinisch manifesten Erkrankung ist die HPV‐Infektion mitunter mit erheblichen Auswirkungen auf die Lebensqualität assoziiert, die Behandlung geht mit einer hohen Rezidivrate einher und invasive Neoplasien (zum Beispiel Zervix‐, Anal‐, Vulva‐, Penis‐, Oropharynxkarzinom) sind zudem durch eine...

article

S2k‐Leitlinie zur Diagnostik und Therapie des Zoster und der Postzosterneuralgie

Gerd E. Gross, Lisa Eisert, Hans Wilhelm Doerr, Helmut Fickenscher, more

JDDG: Journal der Deutschen Dermatologischen Gesellschaft > 18 > 1 > 55 - 79

Diese Leitlinie richtet sich an Dermatologen, Ophthalmologen, HNO‐Ärzte, Pädiater, Neurologen, Virologen sowie Infektiologen, Anästhesisten und Allgemeinmediziner in Klinik und Praxis und dient zur Information für andere medizinische Fachrichtungen, die an der Behandlung des Zoster beteiligt sind. Darüber hinaus soll die Leitlinie Kostenträgern und politischen Entscheidungsträgern zur Orientierung...

article

S2k guidelines for the diagnosis and treatment of herpes zoster and postherpetic neuralgia

Gerd E. Gross, Lisa Eisert, Hans Wilhelm Doerr, Helmut Fickenscher, more

JDDG: Journal der Deutschen Dermatologischen Gesellschaft > 18 > 1 > 55 - 78

The present guidelines are aimed at residents and board‐certified specialists in the fields of dermatology, ophthalmology, ENT, pediatrics, neurology, virology, infectious diseases, anesthesiology, general medicine and any other medical specialties involved in the management of patients with herpes zoster. They are also intended as a guide for policymakers and health insurance funds. The guidelines...

article

A DELPHI study on aspects of study design to overcome knowledge gaps on the burden of disease caused by serogroup B invasive meningococcal disease

Ole Marten, Florian Koerber, David Bloom, Monika Bullinger, more

Health and Quality of Life Outcomes > 2019 > 17 > 1 > 1-9

Background Value assessment of vaccination programs against serogroup B invasive meningococcal disease (IMD) is on the agenda of public health authorities. Current evidence on the burden due to IMD is unfit for pinning down the nature and magnitude of the full social and economic costs of IMD for two reasons. First, the concepts and components that need to be studied are not agreed, and second, measures...

article

Correlation of morphological parameters and visual acuity with neurological development in former preterm children aged 4–10 years

Achim Fieß, Ruth Kölb‐Keerl, Alexander K. Schuster, Markus Knuf, more

Acta Ophthalmologica > 96 > 8 > e1010 - e1017

Purpose The objective of this study was to investigate the relationship between visual acuity, peripapillary retinal nerve fibre layer (pRNFL), retinal thickness at the fovea and other factors with the neurologic status of former preterm children. Methods In this cross‐sectional hospital based study in a maximum care tertiary centre, detailed anthropometric and ophthalmological data of former preterm...

article

MMR and MMRV vaccines

Frank Kowalzik, Jörg Faber, Markus Knuf

Vaccine > 2018 > 36 > 36 > 5402-5407

Measles, mumps, rubella and varicella are viral infections which can implicate seriously long-term sequelae of infected individuals or even the unborn child. Vaccines against the individual diseases have long been available. Global measles vaccination is estimated to have prevented more than 20million deaths during 2000–2015. During the same time period, measles incidence decreased from 146 to 36...

article

Immunization of preterm infants with GSK’s hexavalent combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b conjugate vaccine: A review of safety and immunogenicity

Felix Omeñaca, Liliana Vázquez, Pilar Garcia-Corbeira, Narcisa Mesaros, more

Vaccine > 2018 > 36 > 7 > 986-996

Infants with history of prematurity (<37 weeks gestation) and low birth weight (LBW, <2500 g) are at high risk of infection due to functional immaturity of normal physical and immunological defense mechanisms. Despite current recommendations that infants with history of prematurity/LBW should receive routine immunization according to the same schedule and chronological age as full-term infants,...

article

Prevalence and associated factors of strabismus in former preterm and full-term infants between 4 and 10 Years of age

Achim Fieß, Ruth Kölb-Keerl, Alexander K. Schuster, Markus Knuf, more

BMC Ophthalmology > 2017 > 17 > 1 > 1-9

Background Limited data exist collating most of the associated factors for strabismus in one analysis. The aim of this study was to assess the prevalence of strabismus and to analyse associated factors in former preterm and full-term infants. Methods In this cross-sectional study, 239 former preterm infants with gestational age (GA) ≤ 32 weeks and 264 former full-term born infants with GA ≥ 37 weeks...

article

Macular morphology in former preterm and full-term infants aged 4 to 10 years

Achim Fieß, Johannes Janz, Alexander K. Schuster, Ruth Kölb-Keerl, more

Graefe's Archive for Clinical and Experimental Ophthalmology > 2017 > 255 > 7 > 1433-1442

Objective To analyse macular retinal and choroidal layer thickness in former preterm and full-term infants and to assess associated perinatal influence factors and functional correlation. Methods This prospective controlled, cross-sectional, hospital-based study in a tertiary center of maximum care examined former preterm infants with a gestational age (GA) ≤ 32 weeks and full-term neonates currently...

article

Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses

Michael Fichter, Keti Piradashvili, Anette Pietrzak-Nguyen, Leah Pretsch, more

Biomaterials > 2016 > 108 > C > 1-12

Targeting antigen combined with adjuvants to hepatic antigen-presenting cells (APCs) is essential for the induction of intrahepatic T cellular immunity controlling and resolving viral infections of the liver. Intravenous injection of antigen-loaded nanoparticles is a promising approach for the delivery of antigens to liver APCs. Accordingly, polymeric nanocapsules (NCs) synthesized exclusively of...

article

Corrigendum to “The efficacy of intranasal live attenuated influenza vaccine in children 2 through 17 years of age: A meta-analysis of 8 randomized controlled studies” [Vaccine 30 (2012) 886–892]

Christopher S. Ambrose, Xionghua Wu, Markus Knuf, Peter Wutzler

Vaccine > 2015 > 33 > 39 > 5235

article

Vierfach gegen Grippe: bald Standard?

Peter Wutzler, Brigitte Dietz, Roland Hardt, Lutz Hoins, more

MMW - Fortschritte der Medizin > 2015 > 157 > 15 > 60-65

Der klassische trivalente Grippeimpfstoff enthält – neben zwei Influenza-A-Subtypen – nur einen B-Stamm. Da die Vorhersagen, welche B-Linie in der nächsten Saison aktiv sein wird, nicht immer zutreffen, war die Entwicklung eines Vierfachimpfstoffes naheliegend. Für wen ist er empfehlenswert?

article

Public health impact and cost-effectiveness of intranasal live attenuated influenza vaccination of children in Germany

Oliver Damm, Martin Eichner, Markus Andreas Rose, Markus Knuf, more

The European Journal of Health Economics > 2015 > 16 > 5 > 471-488

In 2011, intranasally administered live attenuated influenza vaccine (LAIV) was approved in the EU for prophylaxis of seasonal influenza in 2–17-year-old children. Our objective was to estimate the potential epidemiological impact and cost-effectiveness of an LAIV-based extension of the influenza vaccination programme to healthy children in Germany. An age-structured dynamic model of influenza transmission...

article

Safety and immunogenicity of an MF59®-adjuvanted A/H1N1 pandemic influenza vaccine in children from three to seventeen years of age

Markus Knuf, Geert Leroux-Roels, Hans. C. Rümke, Katia Abarca, more

Vaccine > 2015 > 33 > 1 > 174-181

This study was designed to identify the optimal dose of an MF59^®-adjuvanted, monovalent, A/H1N1 influenza vaccine in healthy paediatric subjects.Subjects aged 3–8 years (n=194) and 9–17 years (n=160) were randomized to receive two primary doses of A/H1N1 vaccine containing either 3.75μg antigen with half a standard dose of MF59 adjuvant, 7.5μg antigen with a full dose of MF59, or (children 3–8 years...

article

Dendritic cells change IL-27 production pattern during childhood

Claudius U Meyer, Julia Birkholz, Nadine Weins, Aysefa Doganci, more

BMC Research Notes > 2015 > 8 > 1 > 1-3

Background Interleukin-27 (IL-27) has been described to be highly expressed during the very first days after birth, but secretion of IL-27 by dendritic cells during the course of childhood has not been described. Findings In our present study we enrolled children (n = 55) in the range from 1 day of to 18 years of age and asked for a small whole blood sample. The capacity of dendritic cells to produce...

article

Pneumococcal Vaccination in Europe: Schedule Adherence

Alain Gervaix, Filippo Ansaldi, António Brito-Avô, Chiara Azzari, more

Clinical Therapeutics > 2014 > 36 > 5 > 802-812.e1

Nonadherence to recommended pneumococcal conjugate vaccine (PCV) schedules may have implications for protection against pneumococcal disease. In this commentary, we have assessed adherence to the recommended dosing schedules (the completion of the primary PCV and booster series) in different European countries. We found that adherence with the PCV schedule was lower than that for diphtheria-tetanus-acellular...

article

The burden of seasonal and pandemic influenza in infants and children

Bernhard R. Ruf, Markus Knuf

European Journal of Pediatrics > 2014 > 173 > 3 > 265-276

The burden of influenza is unevenly distributed, with more severe outcomes in children aged <5 years than older children and adults. In spite of this, immunisation policies for young children are far from universal. This article provides an overview of the published evidence on the burden of influenza in children worldwide, with a particular interest in the impact of pandemic influenza in 2009–2010...

article

4Flu - an individual based simulation tool to study the effects of quadrivalent vaccination on seasonal influenza in Germany

Martin Eichner, Markus Schwehm, Johannes Hain, Helmut Uphoff, more

BMC Infectious Diseases > 2014 > 14 > 1 > 1-21

Background Influenza vaccines contain Influenza A and B antigens and are adjusted annually to match the characteristics of circulating viruses. In Germany, Influenza B viruses belonged to the B/Yamagata lineage, but since 2001, the antigenically distinct B/Victoria lineage has been co-circulating. Trivalent influenza vaccines (TIV) contain antigens of the two A subtypes A(H3N2) and A(H1N1), yet of...

Publication date

Last 3 years (1)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

INFONA - science communication portal

Search results for: Markus Knuf

Association of viral load with TRAIL, IP‐10, CRP biomarker signature and disease severity in children with respiratory tract infection or fever without source: A prospective, multicentre cohort study

German evidence and consensus‐based (S3) guideline: Vaccination recommendations for the prevention of HPV‐associated lesions

Evidenz‐ und konsensbasierte (S3) Leitlinie: Impfprävention HPV‐assoziierter Neoplasien

S2k‐Leitlinie zur Diagnostik und Therapie des Zoster und der Postzosterneuralgie

S2k guidelines for the diagnosis and treatment of herpes zoster and postherpetic neuralgia

A DELPHI study on aspects of study design to overcome knowledge gaps on the burden of disease caused by serogroup B invasive meningococcal disease

Correlation of morphological parameters and visual acuity with neurological development in former preterm children aged 4–10 years

MMR and MMRV vaccines

Immunization of preterm infants with GSK’s hexavalent combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b conjugate vaccine: A review of safety and immunogenicity

Prevalence and associated factors of strabismus in former preterm and full-term infants between 4 and 10 Years of age

Macular morphology in former preterm and full-term infants aged 4 to 10 years

Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses

Corrigendum to “The efficacy of intranasal live attenuated influenza vaccine in children 2 through 17 years of age: A meta-analysis of 8 randomized controlled studies” [Vaccine 30 (2012) 886–892]

Vierfach gegen Grippe: bald Standard?

Public health impact and cost-effectiveness of intranasal live attenuated influenza vaccination of children in Germany

Safety and immunogenicity of an MF59®-adjuvanted A/H1N1 pandemic influenza vaccine in children from three to seventeen years of age

Dendritic cells change IL-27 production pattern during childhood

Pneumococcal Vaccination in Europe: Schedule Adherence

The burden of seasonal and pandemic influenza in infants and children

4Flu - an individual based simulation tool to study the effects of quadrivalent vaccination on seasonal influenza in Germany

Filter options

Publication date

Content availability

Publication language

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Markus Knuf

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Publication language

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options