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F 2 -isoprostanes are prostaglandin F 2 -like compounds that are formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. Intermediate in the pathway of the formation of isoprostanes are labile prostaglandin H 2 -like bicyclic endoperoxides (H 2 -isoprostanes), which are reduced to F 2 -isoprostanes and also undergo rearrangement in...
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