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J. Neurochem. (2011) 119, 389–397.
Abstractα‐Synuclein causes Parkinson’s disease if mutated or aberrantly produced in neurons. α‐Synuclein–lipid interactions are important for the normal function of the protein, but can also contribute to pathogenesis. We previously reported that deletion of the first 10 N‐terminal amino acids dramatically reduced lipid binding in vitro, as well as membrane binding...
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