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The 3β-hydroxysteroid dehydrogenase (3β-HSD) isoenzymes play a key role in cellular steroid hormone synthesis. Here, a 3β-HSD gene homolog was cloned from Rana grylio virus (RGV), a member of family Iridoviridae. RGV 3β-HSD gene has 1068bp, encoding a 355aa predicted protein. Transcription analyses showed that RGV 3β-HSD gene was transcribed immediate-early during infection from an initiation site...
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