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Background
Distinctive rounded structures termed spherules have been observed in thyroid fine‐needle aspiration (FNA) samples. Although they are often small and interpreted as microfollicles, spherules are notable for the even spacing of the follicular cells along the perimeter of the structure. Because they have an orderly architectural arrangement, it has been hypothesized that spherules are benign...
BACKGROUND
The reclassification of noninvasive follicular variant of papillary thyroid carcinoma as noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (NIFTP) has created diagnostic and management issues for thyroid fine‐needle aspiration (FNA). In response to these challenges, the authors' laboratory adopted a NIFTP policy including 1) stringent criteria (requiring pseudo‐inclusions,...
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