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As described on page 6125, H. Wang and co‐workers design a small molecule that simultaneously self‐assembles into nanofibers in tumor sites and exhibits an assembly‐induced retention (AIR) effect, which results in an improved photoacoustic (PA) imaging signal and enhanced therapeutic efficacy. It is envisaged that the AIR effect based on the assembly of supramolecular structures in living systems...
An assembly‐induced retention effect for enhanced tumor photoacoustic (PA) imaging and therapeutics is described. A responsive small‐molecule precursor is prepared that simultaneously self‐assembles into nanofibers in tumor sites that exhibit an assembly‐induced retention effect, which results in an improved PA imaging signal and enhanced therapeutic efficacy. This successful proof‐of‐concept study...
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