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The effect of advanced glycation end products (AGE-s) was studied on the proliferation and cell death of human skin fibroblasts in culture. Several AGE-products were prepared from proteins, a peptide and amino acids, using Glucose or Fructose, with or without Fe 2+ . The AGE preparations increased cell death at the 7th day, after only 72 hours of incubation. Some of these glycation products...
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