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Both phosphorylated (p) mammalian target of rapamycin (mTOR) and protein S6 kinase 1 (p70 S6K ) are known to regulate protein synthesis and are affected during intrauterine growth restriction (IUGR). We studied the mTOR pathway during hyperthermia (HT)-induced IUGR in sheep.Beginning at 40 days gestational age, 4 ewes were exposed to HT for 55 days and 4 were exposed for 80 days to induce...
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