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Background
A fluorescent probe glutamylprolyl hydroxymethyl rhodamine green (EP‐HMRG), which becomes fluorescent after cleavage by dipeptidyl peptidase‐IV (DPP‐IV), has been reported to be useful for the detection of esophageal cancer. Thus, we investigated whether head and neck squamous cell carcinoma (HNSCC) can be detected by spraying EP‐HMRG.
Methods
Fluorescence imaging of 17 cases of HNSCCs...
Background Detecting superficial head and neck squamous cell carcinoma (HNSCC) by endoscopy is challenging because of limited morphological hallmarks, and iodine cannot be applied to head and neck lesions due to severe mucosal irritation. γ-glutamyltranspeptidase (GGT), a cell surface enzyme, is overexpressed in several cancers, and it has been reported that γ-glutamyl hydroxymethyl rhodamine green...
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