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Cyclooxygenase-2 (COX-2) catalyzes the formation of PGH 2 from arachidonic acid. PGH 2 is further converted to different prostaglandins (PG), such as PGE 2 , PGD 2 and TxB 2 . In this study a rapid online-SPE-LC-MS method for the simultaneous quantification of PGE 2 , PGD 2 and TxB 2 streamlined for COX-2 enzyme assays is presented. Baseline...
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