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Diabetic Retinopathy (DR) is one of the leading causes of blindness amongst the working age population. The presence of microaneurysms (MA) in retinal images is a pathognomonic sign of DR. In this work we have presented a novel combination of algorithms applied to a public dataset for automated detection of MA in colour fundus images of the retina. The proposed technique first detects an initial set...
Automatic segmentation of the retinal vasculature is considered as a first step in computer assisted medical applications related to diagnosis and treatment planning. This paper describes a pixel classification based method of segmenting retinal blood vessels using linear discriminant analysis. The vessel-ness measure of a pixel is defined by the feature vector comprised of a modified multiscale line...
This paper presents a new supervised method for segmentation of blood vessels in retinal images. This method uses an ensemble system of boot strapped decision trees and utilizes a feature vector based on the orientation analysis of gradient vector field, morphological linear transformation, line strength measures and Gabor filter responses. The feature vector encodes information to handle the healthy...
The change in morphology, diameter, branching pattern and/or tortuosity of retinal blood vessels is an important indicator of various clinical disorders of the eye and the body. This paper reports a supervised methodology for segmentation of the retinal vasculature from ocular fundus images. A 7-D feature vector is constructed by computing the outputs of morphological linear operators, line strengths...
The emergence of grid and cloud computing require load balancers to deal with potential problems, such as high level of scalability and heterogeneity of computing resources. In this paper, we present a generic load balancing framework which separates allocating process and migrating process while preserving a guaranteed level of service. Based on this framework, an intelligent load balancer that is...
Automatic retinal blood vessel extraction is very important for early diagnosis and prevention of several retinal diseases. In this paper, a new retinal vasculature segmentation algorithm is proposed based on mathematical morphology, principal curvature, non-maximal suppression and hysteresis thresholding based morphological reconstruction. The blood vessels are enhanced by applying the top-hat transformation...
With contactless inductive power transmission it is possible to transfer electrical energy in industrial, business or consumer electronics over an air gap and therefore avoiding sliding contacts, trailing cables or slip rings. The paper presents a concept for a computer-aided modelling and design of inductive power transmission systems. In this matter the minimisation of power loss and aspects of...
Semantic web links together and defines various parameters leading to user/customer satisfaction. Therefore it is important to identify the aspects of various customer satisfaction areas in online businesses, which can support semantic web. When recollecting about parameters in e-commerce, we will come automatically to the question: 'What are then these parameters ? Where do they lead to? There is...
There is much effort to develop comprehensive support for the storage and querying of XML data in database management systems. The major developers have extended their systems to handle XML data natively. These have the advantage over stand-alone XML database systems that relational and XML data can be queried mutually. Indeed, recent SQL standards specify means to query relational and XML data together...
Mathematical and computational tumor dynamics models can provide considerable insight into the relative importance and interdependence of related biological mechanisms. They may also suggest the existence of optimal treatment windows in the generic setting. Nevertheless, they cannot be translated into clinical practice unless they undergo a strict and thorough clinical validation and adaptation. In...
A consensus seems to have emerged that streams cannot be processed efficiently by relational database engines. This point has been strongly advocated by Michael Stonebreaker, whose StreamBase [19] offers two orders of magnitude better performance in stream processing than a standard DBMS. We faced the challenge and investigated how much improvement in stream processing can be achieved in a standard...
Data management in post-genomic clinical trials is the process of collecting and validating clinical and genomic data with the goal to answer research questions and to preserve it for future scientific investigation. Comprehensive metadata describing the semantics of the data are needed to leverage it for further research like cross-trial analysis. Current clinical trial management systems mostly...
The "Oncosimulator" is at the same time a concept of multilevel integrative cancer and (treatment affected) normal tissue biology, an algorithmic construct and a software tool which aims at supporting the clinician in the process of optimizing cancer treatment on the patient individualized basis. Additionally it is a platform for better understanding and exploring the naturalphenomenon...
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