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Aptamer-based microarrays for the quantitation of multiple protein analytes have been developed. A multiplex aptamer microarray was generated by printing two RNA aptamers (anti-lysozyme and anti-ricin) and two DNA aptamers (anti-IgE and anti-thrombin) on to either streptavidin (SA) or neutravidin (NA)-coated glass slides. However, substantial optimization was required in order to ensure the simultaneous...
Nucleic acid taggants can potentially be used to identify, track, and attribute microbiologicals, including genetically-modified organisms or pathogens. We propose to introduce nucleic acid taggants into bacterial media, and to then recover the taggants in sterilized bacterial waste. Surprisingly, many of the steps that might be suspected to degrade the detection of a nucleic acid taggant, such as...
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