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Topographically localized over-expression of the human Bcl-2 protein in retinal glial Muller cells of a transgenic mice (line 71) leads to early postnatal apoptotic Muller cell death and retinal degeneration. Morphological, immunohistological and confocal laser microscopic examination of transgenic and wild-type retinas were achieved on paraffin retinal sections, postnatally. Apoptosis occurs two...
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