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Prediction of sustained virological response (SVR) during treatment would allow clinicians to identify patients most likely to benefit from therapy.Retrospective analysis of data from 1121 adults with chronic hepatitis C treated for 48 weeks with peginterferon alfa-2a (40KD) 180μg/week plus placebo or ribavirin (1000/1200mg/day), or interferon alfa-2b 3 MIU three times/week plus ribavirin in a randomized,...
Background/Aims: Baseline factors and early decline in serum hepatitis C virus RNA are predictive of sustained virological response to interferon therapy in patients with chronic hepatitis C. We evaluated the prognostic value of baseline factors and early viral RNA among patients treated with peginterferon alfa-2a (40KD).Methods: Data were pooled from three randomized trials involving 814 patients...
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