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The solubility of diphenhydramine hydrochloride (DH) in four pure solvents (methanol, ethanol, acetone and ethyl acetate) and two binary solvents (ethanol+ethyl acetate) and (ethanol+acetone) was determined at temperatures from (278.15 to 323.15)K. The experimental solubility of DH is well correlated by the modified Apelblat equation, the CNIBS/R-K equation and the hybrid model, respectively. All...
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