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The vanilloid receptor 1(VR1) is a nonselective cation channel that is activated by pungent vanilloid compound, extracellular protons, or noxious heat. mRNA of VR1 and vanilloid receptor 1–like receptor (VRL1) were expressed in PC12 cells, and only VR1 mRNA was detected in glioma and A10 cell lines. VR1 protein was demonstrated in PC12 cells by immunocytochemistry and Western blotting. Capsaicin (CPS),...
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