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More and more researches are exploring the neurostimulation effect of ultrasound (US) on the central nervous system (e.g. brain and retina) and the peripheral nervous system (such as skin). US stimulation has been regarded as a new noninvasive neurostimulation approach by many researchers. Our previous studies had shown that the temporal response patterns of RGCs could be stimulated by US in vitro...
The therapeutic effect of chemotherapy of glioblastoma is very limited due to the existence of blood-brain barrier. Focused ultrasound combined with microbubbles is an attractive method to deliver therapeutic agents to brain tissue noninvasively, transiently and locally. Paclitaxel is a potent anti-cancer agent. Thus, the objective of this study is to investigate the therapeutic effect of paclitaxel...
Focused ultrasound combined with microbubbles has shown to be a promising technique to induce noninvasively the localized BBB opening. The purpose of the present study is to explore the potential application of curcumin-loaded polysorbate 80-coated cerasomes (CPC) for treatment of Parkinson's disease using focused ultrasound. The CPC nanoparticles were fabricated and characterized and the optimal...
Previous studies showed that the concentration of ultrasound contrast agents (UCAs) during imaging would impact greatly on the accuracy of flow velocity measurements using ultrasonic particle image velocimetry (Echo PIV) technique. This paper presents a texture-based method to identify the optimum concentration of UCAs for Echo PIV. The first-order and seconded-order texture features, standard deviation,...
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