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Intravascular ultrasound (IVUS) is a well-established diagnostic method that has been applied frequently for providing high-resolution images of vessel wall and atherosclerotic plaques. Side looking transducer has been employed in a catheter for delineating the structure of vessel wall and lesions. However, it is difficult to get the flow distribution in the vessel by side looking transducer as the...
Invasiveness research is an essential step in breast cancer metastasis. The application of non-contact high frequency ultrasound microbeam stimulation (HFUMS) offers a manner of determining the invasion potential of breast cancer cells. In this article, we compare the calcium elevations elicited in breast cancer cells.
We numerically report a high efficient acoustic lens using a flat artificial composite plate in water, which is designed using silicone films deposited on PMMA plate engraved with the annular grooves. The focusing effect is due to the phase of the plate changing with the height of PMMA variation, while the total height of the plate is held constant. As both PMMA and silicone are low impedance mismatch...
Ultrasound (US) brain stimulation has been demonstrated to be a promising approach for noninvasive neuromodulation. However, traditional methods always demand animals to be under anesthesia and body constraint to achieve stable operation with bulky US transducer, while those demands would result in interference to the neural activity related to perception, cognition, and behavior. Appling a miniature...
Intravascular ultrasound (IVUS) is a well-established diagnostic method that provides high-resolution images of vessel walls and atherosclerotic plaques. High-frequency (>50 MHz) ultrasound enables the spatial resolution of IVUS to approach that of optical imaging methods. However, the penetration depth decreases when using higher imaging frequencies due to the greater acoustic attenuation. In...
Invasiveness research is an essential step in breast cancer metastasis. The application of high-frequency ultrasound microbeam stimulation (HFUMS) offers a manner of determining the invasion potential of human breast cancer cells by eliciting the elevation of transient cytoplasmic calcium ions (Ca2+). The fluorescent change in invasive breast cancer cells (MDA-MB-231), reflecting Ca2+ elevation elicited...
Currently, intravascular ultrasound (IVUS) has been frequently used for diagnosing the atherosclerotic plaque due to its good imaging penetration and accurate evaluation. In general, two types of transducers were used for IVUS imaging, i.e. single-element transducer and radial array transducer. It should be noted that imaging resolution of single-element transducer was reduced in the deep area. In...
Atherosclerotic plaque rupture will cause acute coronary syndrome and sudden cardiac death, so that the diagnosis of this kind disease is crucial in clinical studies. Intravascular ultrasound (IVUS) imaging is an effective means of detecting atherosclerotic plaques. In general, two kinds of transducers were used for IVUS imaging, i.e. single-element transducer and radial array transducer. It should...
Ultrasound (US) brain stimulation has been demonstrated to be a promising approach for noninvasive neuromodulation. However, traditional methods always demand animals to be under anesthesia and body constraint to achieve stable operation with bulky US transducer, while those demands would result in interference to the neural activity related to perception, cognition, and behavior. Appling a miniature...
Ultrasound has been demonstrated to be an effective approach for noninvasive neurostimulation. Low frequency ultrasound (<1 MHz) is preferable as its low ultrasonic attenuation when passing through the skull. High frequency ultrasound is able to provide reduced size of focal region. However, the performance of stimulation with high frequency ultrasound is not proved yet. This study examines the...
Micro-ultrasound is an invaluable imaging tool for many clinical and preclinical applications with high resolution (about several tens microns). The imaging systems for micro-ultrasound are developed extensively in recent years including single element imaging systems, and linear array imaging systems. This paper presents the development of a novel programmable and real-time annular array imaging...
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