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Small-animal imaging technology has been rapidly developed for longitudinal screening of laboratory animals raised with disease developments or genetic manipulations. Micro-CT is a noninvasive imaging modality used to assess morphology and function in small-animal imaging. Geometric calibration involves the estimation of a set of parameters that describes the geometry of such systems, and is essential...
The reconstruction images often suffer from artifacts caused by misaligned geometry of flat detector in micro-CT. This paper mainly simulates the causality between the reconstruction image quality and the flat detector geometry by the eight-spheres phantom. The simulation results show that the most influential parameter is β (the rotation angle of the detector plane along the center point O) among...
A high performance micro-tomography (micro-CT) system for insect or small animal imaging has been developed. The system consists of an x-ray source with small focus spot and high brightness, a high precision rotation stage with an object chuck to achieve a cone-beam mode scan, and an x-ray imaging detector. The core of the system is a cooled x-ray imaging detector with high spatial resolution, high...
An X-ray computed tomography (CT) simulator based on Geant4 toolkit was developed for simulation of both fan- and cone-beam CT scanners. There major components X-ray tube, phantom and detector are simulated. Different to analytical simulation, this simulation is accordance with imaging physics by adopting the Geant4 toolkit. Compared with ordinary statistical simulation, acceleration investigation...
The development of more flexible and accurate medical image processing technique and platform is important requirement for clinical diagnosis and treatment. A new interactive image processing method is proposed in this work. Using this method, image smoothing, sharpening, histogram processing, pseudo-color processing, segmentation, reading, local amplification and measurement for medical image in...
With the further application of medical images data in medical field, in order to enrich and enhance the useful information in different medical images, image data fast reading and processing is increasingly becoming a promising research. In this work, we proposed a fast reading and processing method for batch human CT image data. We can use some conventional image processing algorithm for fast processing...
A medical image gray value and coordinate real-time statistics methods based on CT slice data is proposed. By this new method, the gray and three-dimensional coordinate of biomedical image can be successfully observed. We constructed a curve on CT image. The curve could be arbitrary moving, and gray value or 3D coordinate on the curve will be displayed simultaneously. We have obtained the perfect...
Ultrasound diffraction tomography based on Fourier scattering theorem of the lossless circumstance is studied. The relation between resolution and imaging quality is analyzed and a reconstruction algorithm in frequency domain is proposed to reduce storage and computation. Different from an iterative reconstruction method based on NUFFT, we put forward a novel algorithm of interpolation based NUFFT,...
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