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It is crucial to transport foreign substance into living cells efficiently and minimize adverse side-effects. Using ultrasound microbubble, it is possible to enhance the cellular uptake and transfer the extracellular molecules into cells, this process is called sonoporation. However, the spatial location of microbubbles appears to be a stochastic process, which makes the targeted sonoporation at specific...
Transcranial ultrasound is an emerging technology for non-surgical stimulation of the animal and human brain. Previous studies has demonstrated that ultrasound could elicit discharge activity of retinal cells with short latency in animal (Journal of Neuroscience 33(10):4550–4560, 2013) and enhances sensory discrimination abilities of somato-sensory cortex in humans (Nature Neuroscience 17(2):322–9,...
Enhancing the cell's membrane permeability enables to promote foreign substance into the cell and has various applications in biomedical engineering. Sonoporation employs the microbubble inertial cavitation to induce reversible cell-pores in the membranes allowing some impermeable molecules to be transferred into cells. However, the inertial cavitation is the violent collapse of bubbles and thus sonoporation...
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