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Bodipy-verapamil has been tested as a fluorescent substrate for P-glycoprotein-mediated transepithelial secretion in MDCK-C5A epithelia. Net transepithelial secretion (J net ) of [ 3 H]vinblastine from basal-to-apical surfaces of monolayer epithelia is inhibited by taxotere, verapamil and Bodipy-verapamil primarily by a reduction in basal to apical vinblastine (J b ...
Abstract. The in vivo interaction of the lectin Ulex europaeus agglutinin 1 with mouse Peyers patch follicle-associated epithelial cells was studied in the mouse Peyers patch gut loop model by immunofluorescence and electron microscopy. The lectin targets to mouse Peyers patch M-cells and is rapidly endocytosed and transcytosed. These processes are accompanied by morphological changes in the M-cell...
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