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A simple model is developed to describe the instantaneous (rv) and cumulative (Rv) recovery of viruses from water during sample concentration by tangential flow filtration in the regime of constant water recovery, r. A figure of merit, M = rvr, is proposed as an aggregate performance metric that captures both the efficiency of virus recovery and the speed of sample concentration. We derive an expression...
Crossflow membrane filtration is emerging as a concentration method for the recovery and detection of viruses in large volumes of water. To increase virus recovery, an ultrafiltration membrane is usually “blocked” with a proteinaceous solution or a chemical dispersant. This proof-of-concept study explores a novel approach using controlled and rapid (<1h) layer-by-layer adsorption of polyelectrolytes...
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