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Non‐invasive and real‐time monitoring of microcarriers and three‐dimensional cell cultures are important in biomanufacturing and bioprocesses. In article number 2007500, Han Wei Hou and co‐workers introduce a low‐cost microfluidic impedance cytometer with Field's metal electrodes for label‐free and continuous‐flow monitoring of spheroids/microcarriers based on changes in impedance signatures. Potential...
3D cellular spheroids/microcarriers (100 µm–1 mm) are widely used in biomanufacturing, and non‐invasive biosensors are useful to monitor cell quality in bioprocesses. In this work, a novel microfluidic approach for label‐free and continuous‐flow monitoring of single spheroid/microcarrier (hydrogel and Cytodex) based on electrical impedance spectroscopy using co‐planar Field's metal electrodes is reported...
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