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Purpose: The effect of tamoxifen, an antiestrogenic agent, on lipid metabolism was studied in postmenopausal patients with breast cancer who received the drug for postoperative adjuvant treatment following mastectomy.Methods: Fasting blood samples to measure total cholesterol and triglyceride concentrations and postheparin plasma lipase were collected before and 2 months after the initiation of tamoxifen...
Purpose: The study was aimed to examine if eicosapentaenoic acid (EPA), an anti-atherogenic fatty acid increases tissue-type plasminogen activator (tPA) activity in diabetic patients of which decrease has been considered to be one of the causes of increase in coronary artery disease in them. The effect of EPA on an inhibitor of tPA, plasminogen activator inhibitor-1 (PAI-1) was also examined.Method:...
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