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Targeted nanoparticle‐mediated gene therapy for effective melanoma treatment is described by Maling Gou and co‐workers in article number 1800173. Like Hou Yi's arrows to shoot down the extra suns in a famous Chinese myth, the nanoparticle‐mediated gene formulation could efficiently target and kill cancer cells, significantly benefiting the cancer patients.
Oncolytic virus has potential applications in cancer therapy. However, its clinical application is restricted by the virus‐associated biosafety issues. Here, inspired by the key role of vesicular stomatitis virus matrix protein (VSVMP) in the oncolytic vesicular stomatitis virus (VSV) induced apoptosis, a targeted nanoparticle‐delivered neutral VSVMP gene formulation is designed to act like the VSV...
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