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Serotonin(2C) receptors (5-HT 2 C) exert continuous control on the activity of specific populations of neurons in the basal ganglia. While antagonists block the effect of endogenous 5-HT at 5-HT 2C receptors, the actions of inverse agonists may also involve interruption of activity at constitutively active populations of 5-HT 2C receptors. We have evaluated the regional impact...
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