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With the rapid development of nanotechnology, nanoparticles (NPs) are widely used in all fields of life. Nowadays, NPs have shown extraordinary antimicrobial activities and become one of the most popular strategies to combat antibiotic resistance. Whether they are equally effective in combating bacterial persistence, another important reason leading to antibiotic treatment failure, remains unknown...
Osteomyelitis is an inflammatory bone disease caused by infection microorganisms which leads to progressive bone destruction and loss. Drug resistance and inflammatory damage make it urgent to develop new dual‐functional therapies. Based on the powerful bactericidal effect of monocyte/macrophage cells by nature, a functional monocyte with programed anti‐inflammatory ability is promising for osteomyelitis...
Integrating multiple strategies of antibacterial mechanisms into one has been proven to have tremendous promise for improving antimicrobial efficiency. Hence, dual‐valent platinum nanoparticles (dvPtNPs) with a zero‐valent platinum core (Pt0) and bi‐valent platinum shell (Pt2+ ions), combining photothermal and photodynamic therapy, together with “chemotherapy,” emerge as spatiotemporally light‐activatable...
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