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The aim of this study is to evaluate the effect of movement and deformation of red blood cells on therapeutic nanoparticle delivery to tumor tissue through the pores on its vasculature wall. For this purpose, nanoparticle-blood flow through a segment of tumor microvascular is numerically studied. Blood is modeled as a mixture of plasma as a continuous fluid and red blood cell as an elastic solid by...
This study aims to numerically investigate drug delivery to the tumor through the pores in its microvascular wall. A segment of tumor capillaries is modeled as a rigid cylinder with a single pore. Blood flow with nanoparticles is examined by Eulerian–Lagrangian approach in which the blood and particles are modeled as continuous phase and discrete phase, respectively. For investigating of nanoparticle-blood...
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