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The effects of pH and ionic strength (salt concentration) on transmission of single protein human serum albumin (HSA) and human immunoglobulins (HIgG) through a 100 kDa molecular weight cut-off (MWCO) polyethersulfone membrane have been studied using a pulsed sample injection technique. Experimental results obtained clearly demonstrate the effectiveness of changing solution pH and ionic strength optimisation...
In ultrafiltration (UF) processes, the mass transfer coefficient depends on the hydrodynamic shear at the membrane surface. Unfortunately, in all the existing UF test devices, shear stress is non-uniform and only an average value is used. This paper discusses the theory, design, fabrication, and experimental validation of a next-generation cone-and-plate test cell (CPTC) to carry out UF under uniform...
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