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During mandibular movement, condyle is subjected to repetitive compression and the mandibular condylar chondrocytes (MCCs) can detect and respond to this biomechanical environment by altering their metabolism. The present study was undertaken to investigate the effects of pressure to the ultrastructure, aggrecan synthesis, nitric oxide (NO) and prostaglandin F 1 α(PGF 1 α) secretion...
Many signal molecules are involved in mechanotransduction process, among which intracellular calcium and cytoskeleton are two of the most important ones. This study investigated the changes of intracellular calcium and cytoskeleton under pressure and the effects of intracellular calcium variation on cytoskeleton responses to the pressure in rabbit mandibular condylar chondrocytes (MCCs). In vitro...
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