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Rationale The N-methyl D-aspartate antagonist phencyclidine (PCP) is purported to mimic the negative, cognitive and positive symptoms of schizophrenia. Thus, acute and sub-chronic PCP treatment in rodents might produce anhedonia, a decrease in the pleasure produced by rewards. Objectives Experiment 1 investigated whether acute PCP treatment changes the value of sucrose. A comparison was made to...
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