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The aim of the present study is tounderstand the therapeutic effects of recombinant human tumornecrosis factor-α (rH-TNF) on hemocirculation and metabolism ofbrain tumors. Using double-label autoradiographic technique, we havemonitored changes in regional cerebral blood flow (rCBF)and protein-bound fraction of (3H-methyl)-L-methionine, expressed as acid-insolublefraction (AIF), in rat brain tumors...
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