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This study describes a potent activity of Cnidium officinale Makino (Cnidii rhizoma) and Tabanus fulvus Meigan (Tabanus) as an inhibitor of high glucose-induced proliferation of glomerular mesangial cells (GMCs). Raising the ambient glucose concentration from 5.6 to 25mM for 24h caused a dramatic increase in [ 3 H]thymidine incorporation, and these increases were attenuated by treatment of...
Three lignans, which had antagonistic activities of [ 3 H]PAF to washed rabbit platelet receptor binding, were isolated from the fruits of Schisandra chinensis. Schisandrin A showed most potent antagonistic activity against PAF in this group.
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