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Consistent with postmortem data, in a recent positron emission tomography study, we demonstrated less [ 11 C]-(+)-dihydrotetrabenazine ([ 11 C]DTBZ) binding to striatal vesicular monoamine transporter type 2 (VMAT2) in cocaine abusers compared with control subjects. A major limitation of these between-group comparison human studies is their inability to establish a causal relationship...
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