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Studies with targeted mouse mutants are helping to clarify our understanding of cellular mechanisms that underlie memory. Now this approach is also providing tools for resolving controversies about cognitive processes in memory that have perplexed behavioral scientists for many years.
The prominent view that the rodent hippocampus is dedicated to spatial memory has been challenged recently by observations that both limit the nature of hippocampal spatial representation and extend its scope beyond literal space. These findings reveal that the rodent hippocampus mediates memory representations on the basis of non-spatial, as well as spatial, relations among items in memory, and supports...
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