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Abnormal plasticity has been reported in the brain of patients with Parkinson’s disease (PD), especially in the striatum. Although both l-Dopa and dopamine agonist remain to be the mainstay of the treatment in PD, their differential effects on cortical plasticity are unclear. We applied quadripulse stimulation (QPS) over the primary motor cortex (M1) in ten normal subjects to induce bidirectional...
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