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The objective of this study was to evaluate the action of S-nitroso-glutathione (GSNO) on the sporogony and the mRNA expression for EtCRK2 (a cyclin-dependent kinase related protein-2 in Eimeria tenella) during oocyst sporulation. Meanwhile, the effects of GSNO on the sporozoite excystability and infectivity to chickens were also investigated. The results showed that within 10h after the initial sporulation,...
A preliminary study showed that the sporogony process of Eimeria tenella oocysts could be irreversibly inhibited by the S-nitrosothiols, such as S-nitroso-glutathione (GSNO), S-nitroso-N-acetyl-penicillamine. However, the mechanism is unclear at present. In this study the polyacrylamide gel electrophoresis (PAGE) and nitroblue tetrazolium (NBT) photoreduction methods were used to analyze the effects...
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