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To assess the possible association between inherited thrombophilic alterations and the severity of peripheral arterial disease (PAD).A case-control study.We evaluated the presence of G20210A prothrombin (FII) and R506Q FV Leiden mutations, antithrombin, protein C and S deficiencies in 176 patients with PAD at Fontaine's stage II and in 106 patients with critical limb ischaemia (Fontaine's stage III/IV)...
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