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Introduction 5'-deoxy-fluorouridine (5'-DFUR), an analogue of 5-fluorouracil synthesized by Cook et al. in 1976, is used orally to treat stomach, colorectal, cervical, bladder, and breast cancers in Japan. To assess the usefulness of postoperative adjuvant 5'-DFUR chemotherapy in breast cancer, we conducted a controlled comparative study at 153 institutions; control groups received only surgical...
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