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Clinically used Intravascular Ultrasound (IVUS) imaging majorly operates in the 20∼40MHz range, providing resolution on the order of 100μm. Recent reports showed the potential of higher frequency (60–80MHz) of IVUS improving resolution to the level of 30–60μm, but still inferior to the resolution of OCT (10μm). Whether increasing the working frequency a step further could make IVUS comparable to OCT?...
Coronary artery disease remains the leading cause of death and disability in the US. Intravascular ultrasound (IVUS) is one of the standard medical tests routinely performed in hospital to diagnose atherosclerosis by visualizing the structure of affected vessels and identifying the composition of plaques. Optical coherence tomography (OCT) possesses higher resolution to image vulnerable plaque near...
Atherosclerosis is associated with the formation of microvessels in the arterial wall, referred to as vasa vasorum (VV). VV imaging may constitute a new intravascular ultrasound (IVUS) metric of coronary artery plaque vulnerability. The potential of nonlinear contrast IVUS to detect VV in vivo was demonstrated using a prototype transducer with dual-peak frequency response. In this study, we report...
[Pb(Mg1/3Nb2/3)O3]0.63[PbTiO3]0.37 (PMN-PT) free-standing film of comparable piezoelectric properties to bulk material with thickness of 30 µm has been fabricated using a modified precursor coating approach. At 1 kHz, the dielectric permittivity and loss were 4,364 and 0.033, respectively. The remnant polarization and coercive field were 28 µC/cm2 and 18.43 kV/cm. The electromechanical coupling coefficient...
An integrated ultrasound (US) and optical coherence tomography (OCT) probe and system for intravascular imaging has been built. The hybrid dual-function probe is based on a 50 MHz focused ring ultrasound transducer, which has a centric hole for mounting OCT probe. Both focused acoustic and light beams are steered by a 45° mirror for imaging a cross section of vessel. The coaxial probe design enables...
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