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The chronology and history of characterizing the aromatic hydrocarbon [Ah] battery is reviewed. This battery represents the Ah receptor (AHR)-mediated control of at least six, and probably many more, dioxin-inducible genes; two cytochrome P450 genes-P450 1A1 and 1A2 (Cyp1a1, Cyp1a2)-and four non-P450 genes, have experimentally been documented to be members of this battery. Metabolism of endogenous...
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