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Four new steroidal saponins, named ophiopogonin P–S (1–4), together with eleven known ones (5–15) were isolated from the tuberous roots of Ophiopogon japonicus. Their structures were elucidated by spectroscopic and chemical analysis. Compounds 2–15 were evaluated for their cytotoxic activity against five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403 and Hela). Compounds 2, 5, 6, 8 and 9 were...
Two new homoisoflavonoids, named ophiopogonone E (1) and ophiopogonanone H (2), together with thirteen known ones (3–15) were isolated from the tuberous roots of Ophiopogon japonicus. Their structures were elucidated by spectroscopic and chemical analyses. Compounds 7 and 15 were isolated from the genus for the first time. In addition, compounds 2–15 were evaluated for their effects on the inhibition...
Three new steroidal saponins, (25R)‐ruscogenin‐3‐yl α‐L‐rhamnopyranosyl‐(1→2)‐[β‐D‐xylopyranosyl‐(1→4)]‐β‐D‐glucopyranoside (1), diosgenin‐3‐yl 2‐O‐acetyl‐α‐L‐rhamnopyranosyl‐(1→2)‐[β‐D‐xylopyranosyl‐(1→4)]‐β‐D‐glucopyranoside (2), and pennogenin‐3‐yl 2‐O‐acetyl‐α‐L‐rhamnopyranosyl‐(1→2)‐[β‐D‐xylopyranosyl‐(1→4)]‐β‐D‐glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus...
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