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Hepatitis E virus genotype 3 (HEV‐3) can lead to chronic infection in immunocompromised patients, and ribavirin is the treatment of choice. Recently, mutations in the polymerase gene have been associated with ribavirin failure but their frequency before treatment according to HEV‐3 subtypes has not been studied on a large data set. We used single‐molecule real‐time sequencing technology to sequence...
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