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A microfluidic platform integrated with a high-sensitivity surface plasmon resonance (SPR) imaging sensor based on Mach-Zehnder interferometer design is presented. The disposable polydimethylsiloxane (PDMS)-based microfluidic platform consists of four independent flow chambers that can be detected four different concentrated solutions by SPR imaging biosensor simultaneously. The novel feature of the...
This paper reports an automated polymer based microfluidic analysis system integrated with the surface plasmon resonance (SPR) biosensor for qualitatively monitoring of cell adhesion on the sensor surface. Micropumps, microchannels, and SPR biosensor were integrated into a single polymer (PMMA) based microfluidic system. The integrated system has been studied in its potential application in drugs...
An outbreak of severe acute respiratory syndrome (SARS) occurred in China and the first case emerged in mid November 2002. The etiologic agent of this disease was found to be a previously unknown coronavirus, SARS-CoV. The detailed pathology of SARS-CoV infection and the host response to the viral infection are still not known. The 3a gene encodes a non-structural viral protein which is predicted...
This paper reports an automated polymer based microfluidic analysis system integrated with a surface plasm on resonance (SPR) biosensor for detecting the specific binding of biomolecules and qualitatively monitoring of cell adhesion on the sensor surface. Micropumps, microchannels, and a SPR biosensor were integrated into a single polymer (PMMA) based microfluidic system. Because SPR based bio-detection...
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