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Protein sequence motifs information is very important to the analysis of biologically significant regions. The conserved regions have the potential to determine the conformation, function and activities of the proteins. The main purpose of this paper is trying to obtain protein sequence motifs which are universally conserved and across protein family boundaries. Therefore, unlike most popular motif...
Summary form only given. Prediction of protein structures from protein sequences using computers is an important step to discover proteins' 3D conformation structures and their functions and hence has profound theoretical and practical significance in areas such as protein engineering and drug design. In this paper, we discuss our new results in protein secondary structure and transmembrane protein...
Protein secondary structure prediction has a fundamental influence on today's bioinformatics research. In this work, binary and tertiary classifiers of protein secondary structure prediction are implemented on Denoeux belief neural network (DBNN) architecture. Hydrophobicity matrix, orthogonal matrix, BLOSUM62 and PSSM (position specific scoring matrix) are experimented separately as the encoding...
Predicting the secondary structure of a protein (alpha-helix, beta-sheet, coil) is an important step towards elucidating its three dimensional structure, as well as its function. In this research we use a multilayer feed forward neural network for protein secondary structure prediction. The RS126 data set was used for training and testing the proposed neural network. We combined neural network and...
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